Thiobarbituric acid reactive substance (TBARS) a marker of oxidative stress in obstructive sleep apnea

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Oxidative stress in obstructive sleep apnea.

STUDY OBJECTIVES To investigate the relationship between the severity of obstructive sleep apnea (OSA) and oxidative stress, which plays an important role in the pathogenesis of cardiovascular disease, and to elucidate the factors contributing to this relationship. DESIGN Cross-sectional study. PARTICIPANTS A total of 128 consecutive subjects referred to the sleep laboratory of our hospital...

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Is C-reactive protein a marker of obstructive sleep apnea?

BACKGROUND Obstructive sleep apnea (OSA) is a common disease, distinguished by recurrent episodes of upper airway obstruction during sleep, with an inflammatory component. C-reactive protein (CRP) and high-sensitivity C-reactive protein (hs-CRP) are markers of systemic inflammation and may serve as biomarkers of OSA. METHODS Scientific studies published from January 1, 2006, to January 1, 201...

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Cognition and biomarkers of oxidative stress in obstructive sleep apnea

OBJECTIVES The aim of this study was to investigate neuropsychological performance and biomarkers of oxidative stress in patients with obstructive sleep apnea and the relationships between these factors. METHODS This was an observational, cross-sectional study of 14 patients (36.0±6.5 years old) with obstructive sleep apnea and 13 controls (37.3±6.9 years old). All of the participants were cl...

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Oxidative stress inflammation and endothelial dysfunction in obstructive sleep apnea.

Obstructive sleep apnea syndrome (OSA) is a breathing disorder in sleep. In recent years, this entity has emerged as a major public health problem due to its high prevalence and the profound impact on patients' health and quality of life. A large body of evidence identified OSA as an independent risk factor for cardiovascular morbidity and mortality. Also an association was demonstrated with ad...

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Lack of Effect of Sleep Apnea on Oxidative Stress in Obstructive Sleep Apnea Syndrome (OSAS) Patients

PURPOSE The aim of this study was to evaluate markers of systemic oxidative stress and antioxidant capacity in subjects with and without OSAS in order to investigate the most important factors that determine the oxidant-antioxidant status. METHODS A total of 66 subjects referred to our Sleep laboratory were examined by full polysomnography. Oxidative stress and antioxidant activity were asses...

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ژورنال

عنوان ژورنال: Egyptian Journal of Chest Diseases and Tuberculosis

سال: 2014

ISSN: 0422-7638

DOI: 10.1016/j.ejcdt.2013.10.012